Jesinghaus, Moritz;Silva, Miguel Gomes;Zaurito, Antonio Enrico;Brunner, Valentina;Saab, Frederic;Rajamani, Anantharamanan;de Andrade Krätzig, Niklas;Bodenstein, Nicholas;Guillemant, Rémi;Pohl, Junika;Schmitt, Maxime;Öllinger, Rupert;Fusco, Federico;Shakhtour, Julius;Klare, Peter;Janssen, Klaus-Peter;Foersch, Sebastian;Steiger, Katja;Rad, Roland;Pfarr, Nicole;Saur, Dieter;Tschurtschenthaler, Markus
A translational colorectal cancer organoid biobank mirrors patients' tumor histology, molecular profiles, and treatment responses.
J Exp Clin Cancer Res
2026

Chen, Hsin-Hsiang;Tyystjärvi, Sofia;Ruiz Navarro, Diego;Kant, Ravi;Groll, Tanja;Wagner, Ingrid;Domínguez Moreno, Helena;Bonafonte-Pardàs, Irene;Öllinger, Rupert;Afzali, Ali Maisam;Heink, Sylvia;Richter, Lisa Charlotte;Sie, Christopher;Lepennetier, Gildas;Seeholzer, Lea;Steiger, Katja;Merkler, Doron;Rad, Roland;Schotta, Gunnar;Schubert, Benjamin;Muschaweckh, Andreas;Korn, Thomas
CD38 endows local antigen-specific Treg cells with stress resilience for control of compartmentalized CNS inflammation.
Nat Immunol
2026
27
3
516-529

Soberón, Valeria;Osswald, Lena;Moore, Andrew;Sosnowska, Dominika;Swinerd, Gene;Chen, Jingyu;Baygün, Seren;Diehl, Carina;Seyhan, Gönül;Kraus, Laura;Gölling, Vanessa;Trapp, Ricarda;O'Neill, Thomas J;Bortoluzzi, Sabrina;Kovacs, Daniel;Ammon, Tim;Singroul, Pankaj;Hubarzhevska, Yuliia;Öllinger, Rupert;Mueller, Sebastian;Baranov, Olga;Giansanti, Piero;Gillhuber, Felix;Grath, Sonja;Weigert, Oliver;Rosenwald, Andreas;Sasaki, Yoshiteru;Rajewsky, Klaus;Steiger, Katja;Bassermann, Florian;Rad, Roland;Krappmann, Daniel;Ringshausen, Ingo;Schmidt-Supprian, Marc
Correction: Strong constitutive NF-κB signaling in B cells drives SLL/CLL-like lymphomagenesis and overcomes microenvironmental dependencies.
Leukemia
2026
40
3

Amer, Tarek N;Haimovici, Aladin;Kirschnek, Susanne;Vier, Juliane;Moeed, Abdul;Ukachukwu, Uzochukwu;Neugebauer, Daniela;Neubert, Philip;Helmstädter, Martin;Kayser, Severine;Öllinger, Rupert;Rad, Roland;Groß, Olaf;Holzschuh, Jochen;Driever, Wolfgang;Weber, Arnim;Badr, Mohamed Tarek;Häcker, Georg
The second mitochondrial activator of caspases (SMAC) regulates growth, inflammation and mitochondrial integrity in cancer cells.
Cell Death Differ
2026

Soberón, Valeria;Osswald, Lena;Moore, Andrew;Sosnowska, Dominika;Swinerd, Gene;Chen, Jingyu;Baygün, Seren;Diehl, Carina;Seyhan, Gönül;Kraus, Laura;Gölling, Vanessa;Trapp, Ricarda;O'Neill, Thomas J;Bortoluzzi, Sabrina;Kovacs, Daniel;Ammon, Tim;Singroul, Pankaj;Hubarzhevska, Yuliia;Öllinger, Rupert;Mueller, Sebastian;Baranov, Olga;Giansanti, Piero;Gillhuber, Felix;Grath, Sonja;Weigert, Oliver;Rosenwald, Andreas;Sasaki, Yoshiteru;Rajewsky, Klaus;Steiger, Katja;Bassermann, Florian;Rad, Roland;Krappmann, Daniel;Ringshausen, Ingo;Schmidt-Supprian, Marc
Strong constitutive NF-κB signaling in B cells drives SLL/CLL-like lymphomagenesis and overcomes microenvironmental dependencies.
Leukemia
2026
40
3
522-539

Yuan, Detian;Huang, Shan;Berger, Emanuel;Liu, Lei;Gross, Nina;Heinzmann, Florian;Ringelhan, Marc;Connor, Tracy O;Stadler, Mira;Meister, Michael;Weber, Julia;Öllinger, Rupert;Simonavicius, Nicole;Reisinger, Florian;Hartmann, Daniel;Meyer, Rüdiger;Reich, Maria;Seehawer, Marco;Leone, Valentina;Höchst, Bastian;Wohlleber, Dirk;Jörs, Simone;Prinz, Marco;Spalding, Duncan;Protzer, Ulrike;Luedde, Tom;Terracciano, Luigi;Matter, Matthias;Longerich, Thomas;Knolle, Percy;Ried, Thomas;Keitel, Verena;Geisler, Fabian;Unger, Kristian;Cinnamon, Einat;Pikarsky, Eli;Hüser, Norbert;Davis, Roger J;Tschaharganeh, Darjus F;Rad, Roland;Weber, Achim;Zender, Lars;Haller, Dirk;Heikenwalder, Mathias
Kupffer Cell-Derived Tnf Triggers Cholangiocellular Tumorigenesis through JNK due to Chronic Mitochondrial Dysfunction and ROS.
Cancer Cell
2026
44
2
444-447

Mueller, Sebastian;de Andrade Krätzig, Niklas;Tschurtschenthaler, Markus;Silva, Miguel G;Thordsen, Chiara;Trozzo, Riccardo;Simon, Perrine;Saab, Frederic;Kaltenbacher, Thorsten;Zukowska, Magdalena;Lucarelli, Daniele;Öllinger, Rupert;Griger, Joscha;Groß, Nina;Groll, Tanja;Löprich, Jessica;Zaurito, Antonio E;Schömig, Linus R;Bugter, Jeroen M;Bärthel, Stefanie;Falcomatà, Chiara;Strong, Alexander;Brandt, Cordelia;Najajreh, Mulham;Papargyriou, Aristeidis;Maresch, Roman;Collins, Katharina A N;Sailer, David;Schneeweis, Christian;Burger, Sebastian;Fröhlich, Lisa M;Klement, Christine;Belka, Alexander;Montero, Juan J;Jungwirth, Ute;Reichert, Maximilian;Moser, Markus;Neumann, Jens;Vassiliou, George;Cadiñanos, Juan;Varela, Ignacio;Marr, Carsten;Alonso, Daniel F;Lollini, Pier-Luigi;Zhao, Jean;Chesler, Louis;Isacke, Clare M;Riedel, Angela;Braun, Christian J;Sos, Martin L;Beleggia, Filippo;Reinhardt, Hans C;Musteanu, Monica;Barbacid, Mariano;Quante, Michael;Schmidt-Supprian, Marc;Schneider, Günter;Clare, Simon;Lawley, Trevor D;Dougan, Gordon;Steiger, Katja;Conte, Nathalie;Bradley, Allan;Rad, Lena;Saur, Dieter;Rad, Roland
A disease model resource reveals core principles of tissue-specific cancer evolution.
Nature
2026

Frädrich, Julian;Reyes, Carmen Mota;Hendel, Michel;Brunner, Vanessa;Toledo, Batu;Manevski, Damjan;Sommer, Alexander;Häußler, Daniel;Beck, Dominik;Lucarelli, Daniele;Martínez de Villareal, Jaime;Halle, Lennard;Kfuri-Rubens, Raphael;Çifcibaşı, Kaan;Hirschberger, Anna;Öllinger, Rupert;Knolle, Percy A;Steiger, Katja;Rad, Roland;Theis, Fabian J;Real, Francisco X;Bärthel, Stefanie;Böttcher, Jan P;Saur, Dieter;Demir, Ihsan Ekin;Krüger, Achim
Multimodal profiling of pancreatic cancer reveals a TIMP-1-dominated secretory profile determining pro-tumor immunoinstruction in human cancers.
Cell Rep Med
2026
7
1

Proietti, Ludovica;Beltrao, Pedro;Bruna, Alejandra;Cortés-Ciriano, Isidro;Garnett, Mathew J;Gonçalves, Emanuel;Herranz-Ors, Carmen;Kaulich, Manuel;Lord, Christopher J;Petsalaki, Evangelia;Rad, Roland;Ryan, Colm J;Savino, Aurora;Sesia, Debora;Wessels, Lodewyk;Iorio, Francesco
Genetic interactions, synthetic lethality and complexity in cancer vulnerability mapping-Insights and perspectives from the 2nd EuroDepMap symposium.
FEBS Lett
2026