PD-1 instructs a tumor-suppressive metabolic program that restricts glycolysis and restrains AP-1 activity in T cell lymphoma.
Nat. Cancer
2023
4
10
1508-1525
RelB contributes to the survival, migration and lymphomagenesis of B cells with constitutively active CD40 signaling.
Front Immunol
2022
13
Independent Validation and Assay Standardization of Improved Metabolic Biomarker Signature to Differentiate Pancreatic Ductal Adenocarcinoma From Chronic Pancreatitis.
Gastroenterology
2022
163
5
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Spontaneous activity of the mitochondrial apoptosis pathway drives chromosomal defects, the appearance of micronuclei and cancer metastasis through the Caspase-Activated DNAse.
Cell Death Dis
2022
13
4
Intestinal B cells license metabolic T-cell activation in NASH microbiota/antigen-independently and contribute to fibrosis by IgA-FcR signalling.
J Hepatol
2023
79
2
296-313
Tumor-derived prostaglandin E2 programs cDC1 dysfunction to impair intratumoral orchestration of anti-cancer T cell responses.
Immunity
2023
56
6
1341-1358.e11
Transmicron: accurate prediction of insertion probabilities improves detection of cancer driver genes from transposon mutagenesis screens.
Nucleic Acids Res
2023
51
4
Ovulation is triggered by a cyclical modulation of gonadotropes into a hyperexcitable state.
Cell Rep
2023
42
6
Non-canonical functions of SNAIL drive context-specific cancer progression.
Nat Commun
2023
14
1
In vivo interrogation of regulatory genomes reveals extensive quasi-insufficiency in cancer evolution.
Cell Genom
2023
3
3