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Titel:

Basal-Forebrain Cholinergic Nuclei Alterations are Associated With Medication and Cognitive Deficits Across the Schizophrenia Spectrum.

Dokumenttyp:
Journal Article
Autor(en):
Schulz, Julia; Brandl, Felix; Grothe, Michel J; Kirschner, Matthias; Kaiser, Stefan; Schmidt, André; Borgwardt, Stefan; Priller, Josef; Sorg, Christian; Avram, Mihai
Abstract:
BACKGROUND AND HYPOTHESIS: The cholinergic system is altered in schizophrenia. Particularly, patients' volumes of basal-forebrain cholinergic nuclei (BFCN) are lower and correlated with attentional deficits. It is unclear, however, if and how BFCN changes and their link to cognitive symptoms extend across the schizophrenia spectrum, including individuals with at-risk mental state for psychosis (ARMS) or during first psychotic episode (FEP). STUDY DESIGN: To address this question, we assessed vox...     »
Zeitschriftentitel:
Schizophr Bull
Jahr:
2023
Band / Volume:
49
Heft / Issue:
6
Seitenangaben Beitrag:
1530-1541
Volltext / DOI:
doi:10.1093/schbul/sbad118
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/37606273
Print-ISSN:
0586-7614
TUM Einrichtung:
Professur für Neuroradiologie (Prof. Zimmer)
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