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Titel:

Metabolic Derangement of Essential Transition Metals and Potential Antioxidant Therapies.

Dokumenttyp:
Journal Article; Review
Autor(en):
Fontes, Adriana; Jauch, Adrian T; Sailer, Judith; Engler, Jonas; Azul, Anabela Marisa; Zischka, Hans
Abstract:
Essential transition metals have key roles in oxygen transport, neurotransmitter synthesis, nucleic acid repair, cellular structure maintenance and stability, oxidative phosphorylation, and metabolism. The balance between metal deficiency and excess is typically ensured by several extracellular and intracellular mechanisms involved in uptake, distribution, and excretion. However, provoked by either intrinsic or extrinsic factors, excess iron, zinc, copper, or manganese can lead to cellular damag...     »
Zeitschriftentitel:
Int J Mol Sci
Jahr:
2024
Band / Volume:
25
Heft / Issue:
14
Volltext / DOI:
doi:10.3390/ijms25147880
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/39063122
Print-ISSN:
1422-0067
TUM Einrichtung:
Institut für Toxikologie und Umwelthygiene (Prof. Göttlicher)
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