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Title:

Metabolic Derangement of Essential Transition Metals and Potential Antioxidant Therapies.

Document type:
Journal Article; Review
Author(s):
Fontes, Adriana; Jauch, Adrian T; Sailer, Judith; Engler, Jonas; Azul, Anabela Marisa; Zischka, Hans
Abstract:
Essential transition metals have key roles in oxygen transport, neurotransmitter synthesis, nucleic acid repair, cellular structure maintenance and stability, oxidative phosphorylation, and metabolism. The balance between metal deficiency and excess is typically ensured by several extracellular and intracellular mechanisms involved in uptake, distribution, and excretion. However, provoked by either intrinsic or extrinsic factors, excess iron, zinc, copper, or manganese can lead to cellular damag...     »
Journal title abbreviation:
Int J Mol Sci
Year:
2024
Journal volume:
25
Journal issue:
14
Fulltext / DOI:
doi:10.3390/ijms25147880
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/39063122
Print-ISSN:
1422-0067
TUM Institution:
Institut für Toxikologie und Umwelthygiene (Prof. Göttlicher)
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