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Titel:

Comparison of assessment of programmed death-ligand 1 (PD-L1) status in triple-negative breast cancer biopsies and surgical specimens.

Dokumenttyp:
Article; Comparative Study; Journal Article
Autor(en):
Noske, Aurelia; Steiger, Katja; Ballke, Simone; Kiechle, Marion; Oettler, Dirk; Roth, Wilfried; Weichert, Wilko
Abstract:
AIMS: Programmed death-ligand 1 (PD-L1) status in triple-negative breast cancer (TNBC) is important for immune checkpoint inhibitor therapies but may vary between different immunohistochemical assays, scorings and the type of specimen used for analysis. METHODS: We compared the analytical concordance of three clinically relevant PD-L1 assays (VENTANA SP142, VENTANA SP263 and DAKO 22C3 pharmDx) assessing immune cell score (IC), tumour proportion score and combined positive score (CPS) in preopera...     »
Zeitschriftentitel:
J Clin Pathol
Jahr:
2024
Band / Volume:
77
Heft / Issue:
4
Seitenangaben Beitrag:
239-245
Volltext / DOI:
doi:10.1136/jcp-2022-208637
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/36669878
Print-ISSN:
0021-9746
TUM Einrichtung:
Klinik und Poliklinik für Frauenheilkunde (Prof. Kiechle)
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