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Titel:

Elecsys Cerebrospinal Fluid Immunoassays Accurately Detect Alzheimer's Disease Regardless of Concomitant Small Vessel Disease.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't
Autor(en):
Ortner, Marion; Lanz, Korbinian; Goldhardt, Oliver; Müller-Sarnowski, Felix; Diehl-Schmid, Janine; Förstl, Hans; Hedderich, Dennis M; Yakushev, Igor; Logan, Chad A; Weinberger, Jan-Philipp; Simon, Maryline; Grimmer, Timo
Abstract:
BACKGROUND: Differentiating dementia due to small vessel disease (SVD) from dementia due to Alzheimer's disease (AD) with concomitant SVD is challenging in clinical practice. Accurate and early diagnosis of AD is critical to delivering stratified patient care. OBJECTIVE: We characterized the results of Elecsys® cerebrospinal fluid (CSF) immunoassays (Roche Diagnostics International Ltd) in patients with early AD, diagnosed using core clinical criteria, with varying extent of SVD. METHODS: Frozen...     »
Zeitschriftentitel:
J Alzheimers Dis
Jahr:
2023
Band / Volume:
93
Heft / Issue:
4
Seitenangaben Beitrag:
1537-1549
Volltext / DOI:
doi:10.3233/JAD-221187
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/37212102
Print-ISSN:
1387-2877
TUM Einrichtung:
Institut für Geschichte und Ethik der Medizin (Prof. Buyx); Klinik und Poliklinik für Nuklearmedizin (Prof. Weber); Professur für Neuroradiologie (Prof. Zimmer)
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