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Title:

Automated detection of neutralizing SARS-CoV-2 antibodies in minutes using a competitive chemiluminescence immunoassay.

Document type:
Article; Journal Article
Author(s):
Klüpfel, Julia; Paßreiter, Sandra; Rumpf, Melina; Christa, Catharina; Holthoff, Hans-Peter; Ungerer, Martin; Lohse, Martin; Knolle, Percy; Protzer, Ulrike; Elsner, Martin; Seidel, Michael
Abstract:
The SARS-CoV-2 pandemic has shown the importance of rapid and comprehensive diagnostic tools. While there are numerous rapid antigen tests available, rapid serological assays for the detection of neutralizing antibodies are and will be needed to determine not only the amount of antibodies formed after infection or vaccination but also their neutralizing potential, preventing the cell entry of SARS-CoV-2. Current active-virus neutralization assays require biosafety level 3 facilities, while virus...     »
Journal title abbreviation:
Anal Bioanal Chem
Year:
2023
Journal volume:
415
Journal issue:
3
Pages contribution:
391-404
Fulltext / DOI:
doi:10.1007/s00216-022-04416-6
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/36346456
Print-ISSN:
1618-2642
TUM Institution:
Institut für Experimentelle Onkologie und Therapieforschung; Institut für Virologie (Prof. Protzer); Roman Herzog Comprehensive Cancer Center
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