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Title:

Basal-Forebrain Cholinergic Nuclei Alterations are Associated With Medication and Cognitive Deficits Across the Schizophrenia Spectrum.

Document type:
Journal Article
Author(s):
Schulz, Julia; Brandl, Felix; Grothe, Michel J; Kirschner, Matthias; Kaiser, Stefan; Schmidt, André; Borgwardt, Stefan; Priller, Josef; Sorg, Christian; Avram, Mihai
Abstract:
BACKGROUND AND HYPOTHESIS: The cholinergic system is altered in schizophrenia. Particularly, patients' volumes of basal-forebrain cholinergic nuclei (BFCN) are lower and correlated with attentional deficits. It is unclear, however, if and how BFCN changes and their link to cognitive symptoms extend across the schizophrenia spectrum, including individuals with at-risk mental state for psychosis (ARMS) or during first psychotic episode (FEP). STUDY DESIGN: To address this question, we assessed vox...     »
Journal title abbreviation:
Schizophr Bull
Year:
2023
Journal volume:
49
Journal issue:
6
Pages contribution:
1530-1541
Fulltext / DOI:
doi:10.1093/schbul/sbad118
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/37606273
Print-ISSN:
0586-7614
TUM Institution:
Professur für Neuroradiologie (Prof. Zimmer)
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