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Titel:

Helminthic dehydrogenase drives PGE2 and IL-10 production in monocytes to potentiate Treg induction.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't
Autor(en):
Prodjinotho, Ulrich Fabien; Gres, Vitka; Henkel, Fiona; Lacorcia, Matthew; Dandl, Ramona; Haslbeck, Martin; Schmidt, Veronika; Winkler, Andrea Sylvia; Sikasunge, Chummy; Jakobsson, Per-Johan; Henneke, Philipp; Esser-von Bieren, Julia; Prazeres da Costa, Clarissa
Abstract:
Immunoregulation of inflammatory, infection-triggered processes in the brain constitutes a central mechanism to control devastating disease manifestations such as epilepsy. Observational studies implicate the viability of Taenia solium cysts as key factor determining severity of neurocysticercosis (NCC), the most common cause of epilepsy, especially in children, in Sub-Saharan Africa. Viable, in contrast to decaying, cysts mostly remain clinically silent by yet unknown mechanisms, potentially in...     »
Zeitschriftentitel:
EMBO Rep
Jahr:
2022
Band / Volume:
23
Heft / Issue:
5
Volltext / DOI:
doi:10.15252/embr.202154096
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/35357743
Print-ISSN:
1469-221X
TUM Einrichtung:
Institut für Medizinische Mikrobiologie, Immunologie und Hygiene; Klinik und Poliklinik für Neurologie; Lehrstuhl für Molekulare Allergologie und Umweltforschung (Prof. Schmidt-Weber)
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