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Title:

Targeted protein degradation at the host-pathogen interface.

Document type:
Journal Article; Research Support, Non-U.S. Gov't; Review
Author(s):
Grohmann, Christoph; Marapana, Danushka S; Ebert, Gregor
Abstract:
Infectious diseases remain a major burden to global health. Despite the implementation of successful vaccination campaigns and efficient drugs, the increasing emergence of pathogenic vaccine or treatment resistance demands novel therapeutic strategies. The development of traditional therapies using small-molecule drugs is based on modulating protein function and activity through the occupation of active sites such as enzyme inhibition or ligand-receptor binding. These prerequisites result in the...     »
Journal title abbreviation:
Mol Microbiol
Year:
2022
Journal volume:
117
Journal issue:
3
Pages contribution:
670-681
Fulltext / DOI:
doi:10.1111/mmi.14849
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/34816514
Print-ISSN:
0950-382X
TUM Institution:
Institut für Virologie (Prof. Protzer)
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