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Titel:

Targeted protein degradation at the host-pathogen interface.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't; Review
Autor(en):
Grohmann, Christoph; Marapana, Danushka S; Ebert, Gregor
Abstract:
Infectious diseases remain a major burden to global health. Despite the implementation of successful vaccination campaigns and efficient drugs, the increasing emergence of pathogenic vaccine or treatment resistance demands novel therapeutic strategies. The development of traditional therapies using small-molecule drugs is based on modulating protein function and activity through the occupation of active sites such as enzyme inhibition or ligand-receptor binding. These prerequisites result in the...     »
Zeitschriftentitel:
Mol Microbiol
Jahr:
2022
Band / Volume:
117
Heft / Issue:
3
Seitenangaben Beitrag:
670-681
Volltext / DOI:
doi:10.1111/mmi.14849
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/34816514
Print-ISSN:
0950-382X
TUM Einrichtung:
Institut für Virologie (Prof. Protzer)
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