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Title:

Principles of Small-Molecule Transport through Synthetic Nanopores

Document type:
Zeitschriftenaufsatz
Author(s):
Diederichs, T; Ahmad, K.; Burns, J.R.; Nguyen, Q.H.; Siwy,Z.S.; Tornow, M.; Coveney, P.V.; Tampé, R.; Howorka, S.
Abstract:
Synthetic nanopores made from DNA replicate the key biological processes of transporting molecular cargo across lipid bilayers. Understanding transport across the confined lumen of the nanopores is of fundamental interest and of relevance to their rational design for biotechnological applications. Here we reveal the transport principles of organic molecules through DNA nanopores by synergistically combining experiments and computer simulations. Using a highly parallel nanostructured platform, we...     »
Keywords:
DNA nanopore membrane transport single-pore analysis ensemble simulations
Journal title:
ACS Nano 15, 10, 16194–16206 2021-10
Year:
2021
Year / month:
2021-10
Quarter:
4. Quartal
Month:
Oct
Language:
en
Fulltext / DOI:
doi:10.1021/acsnano.1c05139
WWW:
https://pubs.acs.org/doi/10.1021/acsnano.1c05139
Publisher:
American Chemical Society ACS
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