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Titel:

Global Occurrence of Clinically Relevant Hepatitis B Virus Variants as Found by Analysis of Publicly Available Sequencing Data.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't
Autor(en):
Velkov, Stoyan; Protzer, Ulrike; Michler, Thomas
Abstract:
Several viral factors impact the natural course of hepatitis B virus (HBV) infection, the sensitivity of diagnostic tests, or treatment response to interferon-α and nucleos(t)ide analogues. These factors include the viral genotype and serotype but also mutations affecting the HBV surface antigen, basal core promoter/pre-core region, or reverse transcriptase. However, a comprehensive overview of the distribution of HBV variants between HBV genotypes or different geographical locations is lacking....     »
Zeitschriftentitel:
Viruses
Jahr:
2020
Band / Volume:
12
Heft / Issue:
11
Volltext / DOI:
doi:10.3390/v12111344
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/33238650
Print-ISSN:
1999-4915
TUM Einrichtung:
Institut für Virologie
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