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Document type:
Zeitschriftenaufsatz 
Author(s):
Krueger, D.; Gruber, L.; Buhner, S.; Zeller, F.; Langer, R.; Seidl, S.; Michel, K.; Schemann, M. 
Title:
The multi-herbal drug {STW} 5 ({Iberogast}) has prosecretory action in the human intestine. 
Abstract:
There is growing evidence that STW 5 (Iberogast), fixed combination of hydroethanolic herbal extracts), besides being effective in functional dyspepsia, also improves symptoms in irritable bowel syndrome (IBS). Clinical data indicate that modulation of mucosal secretion is a promising approach to treat intestinal disorders associated with IBS. We therefore explored the effect of STW 5 on secretion in the human intestine and the mechanisms by which it acts. The Ussing chamber technique was use...    »
 
Keywords:
Aged, 80 and over, Humans, Aged, Female, Male, Middle Aged, Cell Line, Neurons/metabolism, Plant Extracts/*pharmacology, Epithelial Cells/cytology/drug effects/metabolism, Intestinal Mucosa/*drug effects/innervation/*secretion, Ion Channel Gating/drug effects 
Journal title:
Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 
Year:
2009 
Journal volume:
21 
Month:
nov 
Journal issue:
11 
Pages contribution:
1203--e110 
Language:
eng 
Print-ISSN:
1365-2982 1350-1925