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Titel:

The Helicobacter pylori Type IV Secretion System Encoded by the cag Pathogenicity Island: Architecture, Function, and Signaling.

Dokumenttyp:
Journal Article
Autor(en):
Backert, Steffen; Haas, Rainer; Gerhard, Markus; Naumann, Michael
Abstract:
Various gram-negative pathogens express type IV secretion systems (T4SSs) which translocate bacterial virulence factors into host target cells to hijack cellular processes for their own benefit and causing disease. The pathology of Helicobacter pylori, the causative agent of chronic gastritis, peptic ulcer disease, and gastric cancer in humans, strongly depends on a T4SS encoded by the cag pathogenicity island (cagPAI). This T4SS represents a pilus-like structure and a membrane-spanning complex....     »
Zeitschriftentitel:
Curr Top Microbiol Immunol
Jahr:
2017
Band / Volume:
413
Seitenangaben Beitrag:
187-220
Sprache:
eng
Volltext / DOI:
doi:10.1007/978-3-319-75241-9_8
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/29536360
Print-ISSN:
0070-217X
TUM Einrichtung:
Institut für Medizinische Mikrobiologie, Immunologie und Hygiene
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