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Titel:

Assembly of the postsynaptic membrane at the neuromuscular junction: paradigm lost.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't; Review; Review
Autor(en):
Kummer, TT; Misgeld, T; Sanes, JR
Abstract:
Studies of the vertebrate skeletal neuromuscular junction led to an influential model of how neurotransmitter receptors accumulate in the postsynaptic membrane. In this model, motor axons organize postsynaptic development by secreting neuregulin to induce acetylcholine receptor gene transcription in specialized subsynaptic nuclei, agrin to cluster diffuse receptors in the postsynaptic membrane, and acetylcholine to evoke electrical activity that promotes synaptic maturation. However, new studies...     »
Zeitschriftentitel:
Curr Opin Neurobiol
Jahr:
2006
Band / Volume:
16
Heft / Issue:
1
Seitenangaben Beitrag:
74-82
Sprache:
eng
Volltext / DOI:
doi:10.1016/j.conb.2005.12.003
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/16386415
Print-ISSN:
0959-4388
TUM Einrichtung:
Institut für Neurowissenschaften
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