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Titel:

Lack of RUNX3 regulation in human gastric cancer.

Dokumenttyp:
Journal Article
Autor(en):
Friedrich, MJ; Rad, R; Langer, R; Voland, P; Hoefler, H; Schmid, RM; Prinz, C; Gerhard, M
Abstract:
It has been proposed that the transcription factor RUNX3 is the product of a gastric tumour suppressor gene. We examined RUNX3 expression in gastric biopsies from 105 patients with different histological presentations. Surprisingly, immunohistochemical staining detected RUNX3 protein expression only in infiltrating leukocytes but not in the gastric epithelium. Using laser capture microdissection and quantitative reverse transcription-polymerase chain reaction, we confirmed that the level of RUNX...     »
Zeitschriftentitel:
J Pathol
Jahr:
2006
Band / Volume:
210
Heft / Issue:
2
Seitenangaben Beitrag:
141-6
Sprache:
eng
Volltext / DOI:
doi:10.1002/path.2042
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/16917803
Print-ISSN:
0022-3417
TUM Einrichtung:
II. Medizinische Klinik und Poliklinik (Gastroenterologie); Institut für Allgemeine Pathologie und Pathologische Anatomie
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