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Title:

[Radiotherapy in benign diseases: Morbus Peyronie]

Document type:
Journal Article; Article
Author(s):
Meineke, V; Uebler, C; Köhn, FM; Hofmann, H; Cordes, N; Ring, J; Vogt, HJ
Abstract:
PURPOSE: The induratio penis plastica (IPP) or the so-called Morbus Peyronie is a burdening disease for patients with three main symptoms, induration, deviation and pain. The etiology of this fibrosing and plaque forming disease is largely unknown up to now. PATIENTS AND METHODS: The presented data refer to a retrospective univariant examination of 67 patients, which have been treated for IPP with soft X-rays in the Dermatological Clinic of the Technical University of Munich between 1990 and 1995. The aim of the study was to examine, how far a progression of the disease can be stopped with soft X-rays and how the pain symptomatic is reduced. RESULTS: In 58 of 67 examined patients (86.6%) a progression of the disease could be stopped. 25 out of 67 patients (37.3%) complained of pain before therapy. This symptomatic mostly improved totally in 21 patients (84% of the patients with pain). A complete or partial dissolution of the indurations was to be noticed in 41 of 70 indurations (58.6%). In 23 of 60 patients (38.3%) an improvement or totally regression of the deviation was observed. It could be shown that therapeutic outcome significantly correlates to a shorter duration of anamnesis (p < 0.05), smaller plaque size (p < 0.025) and a tendency to lower age of the patients. CONCLUSION: Radiotherapy of Morbus Peyronie is extremely effective and has a low rate of side effects.
Journal title abbreviation:
Strahlenther Onkol
Year:
2003
Journal volume:
179
Journal issue:
3
Pages contribution:
181-6
Language:
de
Fulltext / DOI:
doi:10.1007/s00066-003-0984-5
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/12627261
Print-ISSN:
0179-7158
TUM Institution:
Klinik und Poliklinik für Dermatologie und Allergologie
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