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Titel:

Synaptic dynamics and neuronal network connectivity are reflected in the distribution of times in Up states.

Dokumenttyp:
Journal Article; Article
Autor(en):
Dao Duc, Khanh; Parutto, Pierre; Chen, Xiaowei; Epsztein, Jérôme; Konnerth, Arthur; Holcman, David
Abstract:
The dynamics of neuronal networks connected by synaptic dynamics can sustain long periods of depolarization that can last for hundreds of milliseconds such as Up states recorded during sleep or anesthesia. Yet the underlying mechanism driving these periods remain unclear. We show here within a mean-field model that the residence time of the neuronal membrane potential in cortical Up states does not follow a Poissonian law, but presents several peaks. Furthermore, the present modeling approach al...     »
Zeitschriftentitel:
Front Comput Neurosci
Jahr:
2015
Band / Volume:
9
Seitenangaben Beitrag:
96
Sprache:
eng
Volltext / DOI:
doi:10.3389/fncom.2015.00096
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/26283956
TUM Einrichtung:
Institut für Neurowissenschaften
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