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Titel:

Linear integration of spine Ca2+ signals in layer 4 cortical neurons in vivo.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't; Article
Autor(en):
Jia, Hongbo; Varga, Zsuzsanna; Sakmann, Bert; Konnerth, Arthur
Abstract:
Sensory information reaches the cortex through synchronously active thalamic axons, which provide a strong drive to layer 4 (L4) cortical neurons. Because of technical limitations, the dendritic signaling processes underlying the rapid and efficient activation of L4 neurons in vivo remained unknown. Here we introduce an approach that allows the direct monitoring of single dendritic spine Ca(2+) signals in L4 spiny stellate cells of the vibrissal mouse cortex in vivo. Our results demonstrate that...     »
Zeitschriftentitel:
Proc Natl Acad Sci U S A
Jahr:
2014
Band / Volume:
111
Heft / Issue:
25
Seitenangaben Beitrag:
9277-82
Sprache:
eng
Volltext / DOI:
doi:10.1073/pnas.1408525111
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/24927564
Print-ISSN:
0027-8424
TUM Einrichtung:
Institut für Neurowissenschaften
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