Atomic force microscopy (AFM) with single polymers allowed to gain new insights into molecular mechanisms of adhesion. Biomolecules were covalently coupled to AFM cantilever tips and their desorption forces from surfaces in liquid environment were measured. This allowed to determine the kinetic parameters of polyhomopeptide desorption from hydrophobic surfaces and lipid bilayers. In addition, adhesion of mussel inspired biomimetic adhesives on metal oxides allowed to delineate the various mechanisms of catechol mediated binding.
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Atomic force microscopy (AFM) with single polymers allowed to gain new insights into molecular mechanisms of adhesion. Biomolecules were covalently coupled to AFM cantilever tips and their desorption forces from surfaces in liquid environment were measured. This allowed to determine the kinetic parameters of polyhomopeptide desorption from hydrophobic surfaces and lipid bilayers. In addition, adhesion of mussel inspired biomimetic adhesives on metal oxides allowed to delineate the various mechan...
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