It has been shown in several studies that erythropoietin improves cardiac function within the setting of acute myocardial infarction. However, a rise in thrombembolic events was also observed. Therefore patients received high-dose EPO or Placebo shortly after myocardial infarction and stenting in a substudy of the REVIVAL-3 study. No difference could be shown in platelet aggregation, measured by impedance-aggregometry in whole blood and no rise of platelet counts was observed. A diminution of platelet aggregation could be seen in both groups, which is attributed to dual platelet inhibition with acetylsalicylic acid and clopidogrel.
«
It has been shown in several studies that erythropoietin improves cardiac function within the setting of acute myocardial infarction. However, a rise in thrombembolic events was also observed. Therefore patients received high-dose EPO or Placebo shortly after myocardial infarction and stenting in a substudy of the REVIVAL-3 study. No difference could be shown in platelet aggregation, measured by impedance-aggregometry in whole blood and no rise of platelet counts was observed. A diminution of pl...
»