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Title:

Neoplastic cell percentage estimation in tissue samples for molecular oncology: recommendations from a modified Delphi study.

Document type:
Journal Article
Author(s):
Dufraing, K; van Krieken, J H; De Hertogh, G; Hoefler, G; Oniscu, A; Kuhlmann, T P; Weichert, W; Marchiò, C; Ristimäki, A; Ryska, A; Scoazec, J Y; Dequeker, E
Abstract:
AIMS: Results from external quality assessment revealed considerable variation in neoplastic cell percentages (NCP) estimation in samples for biomarker testing. As molecular biology tests require a minimal NCP, overestimations may lead to false negative test results. We aimed to develop recommendations to improve the NCP determination in a prototypical entity - colorectal carcinoma - that can be adapted for other cancer types. METHODS AND RESULTS: A modified Delphi study was conducted to reach c...     »
Journal title abbreviation:
Histopathology
Year:
2019
Journal volume:
75
Journal issue:
3
Pages contribution:
312-319
Fulltext / DOI:
doi:10.1111/his.13891
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/31054167
Print-ISSN:
0309-0167
TUM Institution:
Institut für Allgemeine Pathologie und Pathologische Anatomie
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