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Title:

Wide-field and two-photon imaging of brain activity with voltage- and calcium-sensitive dyes.

Document type:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
Author(s):
Homma, R; Baker, BJ; Jin, L; Garaschuk, O; Konnerth, A; Cohen, LB; Zecevic, D
Abstract:
This review presents three examples of using voltage- or calcium-sensitive dyes to image the activity of the brain. Our aim is to discuss the advantages and disadvantages of each method with particular reference to its application to the study of the brainstem. Two of the examples use wide-field (one-photon) imaging; the third uses two-photon scanning microscopy. Because the measurements have limited signal-to-noise ratio, the paper also discusses the methodological aspects that are critical fo...     »
Journal title abbreviation:
Philos Trans R Soc Lond B Biol Sci
Year:
2009
Journal volume:
364
Journal issue:
1529
Pages contribution:
2453-67
Language:
eng
Fulltext / DOI:
doi:10.1098/rstb.2009.0084
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/19651647
Print-ISSN:
0962-8436
TUM Institution:
Institut für Neurowissenschaften
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