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Title:

Activity-dependent plasticity of developing climbing fiber-Purkinje cell synapses.

Document type:
Journal Article; Research Support, Non-U.S. Gov't; Review
Author(s):
Bosman, LW; Konnerth, A
Abstract:
Elimination of redundant synapses and strengthening of the surviving ones are crucial steps in the development of the nervous system. Both processes can be readily followed at the climbing fiber to Purkinje cell synapse in the cerebellum. Shortly after birth, around five equally strong climbing fiber synapses are established. Subsequently, one of these five synaptic connections starts to grow in size and synaptic strength, while the others degenerate and eventually disappear. Both the eliminatio...     »
Journal title abbreviation:
Neuroscience
Year:
2009
Journal volume:
162
Journal issue:
3
Pages contribution:
612-23
Language:
eng
Fulltext / DOI:
doi:10.1016/j.neuroscience.2009.01.032
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/19302832
Print-ISSN:
0306-4522
TUM Institution:
Institut für Neurowissenschaften
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