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Titel:

Activity-dependent plasticity of developing climbing fiber-Purkinje cell synapses.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't; Review
Autor(en):
Bosman, LW; Konnerth, A
Abstract:
Elimination of redundant synapses and strengthening of the surviving ones are crucial steps in the development of the nervous system. Both processes can be readily followed at the climbing fiber to Purkinje cell synapse in the cerebellum. Shortly after birth, around five equally strong climbing fiber synapses are established. Subsequently, one of these five synaptic connections starts to grow in size and synaptic strength, while the others degenerate and eventually disappear. Both the eliminatio...     »
Zeitschriftentitel:
Neuroscience
Jahr:
2009
Band / Volume:
162
Heft / Issue:
3
Seitenangaben Beitrag:
612-23
Sprache:
eng
Volltext / DOI:
doi:10.1016/j.neuroscience.2009.01.032
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/19302832
Print-ISSN:
0306-4522
TUM Einrichtung:
Institut für Neurowissenschaften
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