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Titel:

Genome-wide linkage analysis of serum creatinine in three isolated European populations.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't
Autor(en):
Pattaro, C; Aulchenko, YS; Isaacs, A; Vitart, V; Hayward, C; Franklin, CS; Polasek, O; Kolcic, I; Biloglav, Z; Campbell, S; Hastie, N; Lauc, G; Meitinger, T; Oostra, BA; Gyllensten, U; Wilson, JF; Pichler, I; Hicks, AA; Campbell, H; Wright, AF; Rudan, I; van Duijn, CM; Riegler, P; Marroni, F; Pramstaller, PP
Abstract:
There is increasing evidence for a role of genetic predisposition in the etiology of kidney disease, but linkage scans have been poorly replicated. Here we performed a genome-wide linkage analysis of serum creatinine on 2859 individuals from isolated villages in South Tyrol (Italy), Rucphen (The Netherlands) and Vis Island (Croatia), populations that have been stable and permanently resident in their region. Linkage of serum creatinine levels to loci on chromosomes 7p14, 9p21, 11p15, 15q15-21, 1...     »
Zeitschriftentitel:
Kidney Int
Jahr:
2009
Band / Volume:
76
Heft / Issue:
3
Seitenangaben Beitrag:
297-306
Sprache:
eng
Volltext / DOI:
doi:10.1038/ki.2009.135
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/19387472
Print-ISSN:
0085-2538
TUM Einrichtung:
Institut für Humangenetik
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