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Titel:

Functional surfaces of the hepatitis B virus capsid.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't
Autor(en):
Pairan, A; Bruss, V
Abstract:
The hepatitis B virus (HBV) core protein (CP) forms the shell of an icosahedral nucleocapsid. In a former work, we identified 11 amino acid residues of CP exposed on the capsid surface by an alanine mutation scan as being important for capsid envelopment. We now introduced several other amino acids at six of these positions and found that almost all 27 tested point mutations at S17, K96, and I126 reproduced the phenotype of the alanine mutation (with only two exceptions): the formation of nucleo...     »
Zeitschriftentitel:
J Virol
Jahr:
2009
Band / Volume:
83
Heft / Issue:
22
Seitenangaben Beitrag:
11616-23
Sprache:
eng
Volltext / DOI:
doi:10.1128/JVI.01178-09
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/19710138
Print-ISSN:
0022-538X
TUM Einrichtung:
Institut für Virologie
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