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Title:

Homosynaptic long-term synaptic potentiation of the "winner" climbing fiber synapse in developing Purkinje cells.

Document type:
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
Author(s):
Bosman, LW; Takechi, H; Hartmann, J; Eilers, J; Konnerth, A
Abstract:
During the developmental formation of neuronal circuits, redundant synapses are eliminated and persisting synapses strengthened. In the immature cerebellum, climbing fiber-Purkinje cell synapses undergo a pronounced synaptic rewiring, from a multiple innervation around birth to a mono-innervation in adults. An early stage of this process consists in the differentiation of initially equally strong synapses into one "large" and several "small" synaptic inputs. By performing whole-cell recordings i...     »
Journal title abbreviation:
J Neurosci
Year:
2008
Journal volume:
28
Journal issue:
4
Pages contribution:
798-807
Language:
eng
Fulltext / DOI:
doi:10.1523/JNEUROSCI.4074-07.2008
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/18216188
Print-ISSN:
0270-6474
TUM Institution:
Institut für Neurowissenschaften
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