This work presents a holistic approach to better understand biofilm formation of S. xylosus and its impact on occupation of and persistence in natural and man-made habitats. Adherence and exopolymer biosynthesis of S. xylosus are mostly polysaccharide independent and rather reliant on proteins and eDNA. Biofilm formation is strain-specific, influenced by environmental factors and dependent on the newly characterized protein SxsA. S. xylosus harbors strong barriers to genetic manipulation, among others a new variant of type I RM systems composed of two specificity subunits (hsdRSMS).
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This work presents a holistic approach to better understand biofilm formation of S. xylosus and its impact on occupation of and persistence in natural and man-made habitats. Adherence and exopolymer biosynthesis of S. xylosus are mostly polysaccharide independent and rather reliant on proteins and eDNA. Biofilm formation is strain-specific, influenced by environmental factors and dependent on the newly characterized protein SxsA. S. xylosus harbors strong barriers to genetic manipulation, among...
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