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Titel:

Expression patterns of transcribed human endogenous retrovirus HERV-K(HML-2) loci in human tissues and the need for a HERV Transcriptome Project.

Dokumenttyp:
Journal Article; Research Support, Non-U.S. Gov't; Article
Autor(en):
Flockerzi, A; Ruggieri, A; Frank, O; Sauter, M; Maldener, E; Kopper, B; Wullich, B; Seifarth, W; Müller-Lantzsch, N; Leib-Mösch, C; Meese, E; Mayer, J
Abstract:
BACKGROUND: A significant proportion of the human genome is comprised of human endogenous retroviruses (HERVs). HERV transcripts are found in every human tissue. Expression of proviruses of the HERV-K(HML-2) family has been associated with development of human tumors, in particular germ cell tumors (GCT). Very little is known about transcriptional activity of individual HML-2 loci in human tissues, though. RESULTS: By employing private nucleotide differences between loci, we assigned approximate...     »
Zeitschriftentitel:
BMC Genomics
Jahr:
2008
Band / Volume:
9
Seitenangaben Beitrag:
354
Sprache:
eng
Volltext / DOI:
doi:10.1186/1471-2164-9-354
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/18664271
TUM Einrichtung:
Institut für Virologie
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