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Document type:
Journal Article; Research Support, Non-U.S. Gov't; Article 
Author(s):
Spuentrup, E; Katoh, M; Buecker, A; Fausten, B; Wiethoff, AJ; Wildberger, JE; Haage, P; Parsons, EC; Botnar, RM; Graham, PB; Vettelschoss, M; Günther, RW 
Title:
Molecular MR imaging of human thrombi in a swine model of pulmonary embolism using a fibrin-specific contrast agent. 
Abstract:
OBJECTIVE: Molecular targeted MR imaging of human clots material in a model of pulmonary embolism using a fibrin-specific magnetic resonance imaging contrast agent (EP-2104R, EPIX Pharmaceuticals, Cambridge, MA). MATERIAL AND METHODS: Fresh ex vivo engineered thrombi (human blood) and human clots removed from patients were delivered in 11 swine. Molecular MR imaging with a 3D gradient-echo [3D fast field echo (3DFFE)] sequence and a navigator-gated and cardiac-triggered 3D inversion-recovery bla...    »
 
Journal title abbreviation:
Invest Radiol 
Year:
2007 
Journal volume:
42 
Journal issue:
Pages contribution:
586-95 
Language:
eng 
Print-ISSN:
0020-9996 
TUM Institution:
Klinik und Poliklinik für Nuklearmedizin