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Titel:

Testing of antidotes for organophosphorus compounds: Experimental procedures and clinical reality.

Dokumenttyp:
Journal Article
Autor(en):
Eyer, P; Szinicz, L; Thiermann, H; Worek, F; Zilker, T
Abstract:
According to current knowledge, inhibition of acetylcholinesterase (AChE) is a very important toxic action of organphosphorus compounds (OP). Hence, it is obvious to follow the AChE activity in order to quantify the degree of inhibition and to assess possible reactivation. Red blood cell (RBC)-AChE provides an easily accessible source to follow the AChE status also in humans. There are many reports underlining the appropriateness of RBC-AChE as a surrogate parameter that mirrors the synaptic enz...     »
Zeitschriftentitel:
Toxicology
Jahr:
2007
Band / Volume:
233
Heft / Issue:
1-3
Seitenangaben Beitrag:
108-19
Sprache:
eng
Volltext / DOI:
doi:10.1016/j.tox.2006.08.033
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/17010492
Print-ISSN:
0300-483X
TUM Einrichtung:
2. Medizinische Klinik Toxikologische Abteilung (alt) (Prof. Zilker)
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