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Titel:

Enteral exsorption of acetaminophen after intravenous injection in rats: influence of activated charcoal on this clearance path.

Dokumenttyp:
Journal Article; Article
Autor(en):
Eyer, F; Jung, N; Neuberger, H; Schulz, R; Steiner, K; Ladstetter, B; Poethko, T; Henke, J; Zilker, T
Abstract:
The fate of acetaminophen after intravenous injection in whole bowel-irrigated rats (n = 40) and the influence of activated charcoal on the kinetics were investigated. After randomization to four groups (n = 10, each group), plasma concentration and the quantities of acetaminophen and metabolites excreted into bile, urine and intestine were determined using an in vivo model with or without orally administered activated charcoal and with or without bile duct cannulation. The cumulative amount of...     »
Zeitschriftentitel:
Basic Clin Pharmacol Toxicol
Jahr:
2007
Band / Volume:
101
Heft / Issue:
3
Seitenangaben Beitrag:
163-71
Sprache:
eng
Volltext / DOI:
doi:10.1111/j.1742-7843.2007.00107.x
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/17697035
Print-ISSN:
1742-7835
TUM Einrichtung:
2. Medizinische Klinik Toxikologische Abteilung (alt) (Prof. Zilker); Klinik und Poliklinik für Nuklearmedizin
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