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Title:

Long-term HIV-1 infection of neural progenitor populations.

Document type:
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
Author(s):
Rothenaigner, I; Kramer, S; Ziegler, M; Wolff, H; Kleinschmidt, A; Brack-Werner, R
Abstract:
BACKGROUND: HIV can reside in the brain for many years. While astrocytes are known to tolerate long-term HIV infection, the potential of other neural cell types to harbour HIV is unclear. OBJECTIVE: To investigate whether HIV can persist in neural progenitor cell populations. DESIGN: A multipotent human neural stem cell line (HNSC.100) was used to compare HIV infection in neural progenitor and astrocyte cell populations. METHODS: Expression of cellular genes/proteins was analysed by real-time re...     »
Journal title abbreviation:
AIDS
Year:
2007
Journal volume:
21
Journal issue:
17
Pages contribution:
2271-81
Language:
eng
Fulltext / DOI:
doi:10.1097/QAD.0b013e3282f12f27
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/18090275
Print-ISSN:
0269-9370
TUM Institution:
Institut für Virologie
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