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Title:

Modeling a layer 4-to-layer 2/3 module of a single column in rat neocortex: interweaving in vitro and in vivo experimental observations.

Document type:
In Vitro; Journal Article; Research Support, Non-U.S. Gov't
Author(s):
Sarid, L; Bruno, R; Sakmann, B; Segev, I; Feldmeyer, D
Abstract:
We report a step in constructing an in silico model of a neocortical column, focusing on the synaptic connection between layer 4 (L4) spiny neurons and L2/3 pyramidal cells in rat barrel cortex. It is based first on a detailed morphological and functional characterization of synaptically connected pairs of L4-L2/3 neurons from in vitro recordings and second, on in vivo recordings of voltage responses of L2/3 pyramidal cells to current pulses and to whisker deflection. In vitro data and a detaile...     »
Journal title abbreviation:
Proc Natl Acad Sci U S A
Year:
2007
Journal volume:
104
Journal issue:
41
Pages contribution:
16353-8
Language:
eng
Fulltext / DOI:
doi:10.1073/pnas.0707853104
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/17913876
Print-ISSN:
0027-8424
TUM Institution:
Institut für Neurowissenschaften
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