Login
- Titel:
Ten recently identified associations between nsSNPs and colorectal cancer could not be replicated in German families.
- Dokumenttyp:
- Journal Article; Research Support, Non-U.S. Gov't
- Autor(en):
- Frank, B; Burwinkel, B; Bermejo, JL; Försti, A; Hemminki, K; Houlston, R; Mangold, E; Rahner, N; Friedl, W; Friedrichs, N; Buettner, R; Engel, C; Loeffler, M; Holinski-Feder, E; Morak, M; Keller, G; Schackert, HK; Krüger, S; Goecke, T; Moeslein, G; Kloor, M; Gebert, J; Kunstmann, E; Schulmann, K; Rüschoff, J; Propping, P
- Abstract:
- Ten non-synonymous single nucleotide polymorphisms (nsSNPs), which were recently associated with colorectal cancer risk in a comprehensive, array based study (AKAP9 M463I, DKK3 G335R, AMPD1 Q12X, LIPC L356F, PSMB9 V32I, THBS1 N700S, CA6 S90G, ASCC3 C1995S, DHX36 S416C and CPA4 G303C) were re-evaluated in the present study based on 626 German familial non-HNPCC colorectal cancer patients and 736 healthy controls. No associations of any of the 10 nsSNPs with colorectal cancer could be replicated.... »
- Zeitschriftentitel:
- Cancer Lett
- Jahr:
- 2008
- Band / Volume:
- 271
- Heft / Issue:
- 1
- Seitenangaben Beitrag:
- 153-7
- Sprache:
- eng
- Volltext / DOI:
- doi:10.1016/j.canlet.2008.05.043
- PubMed:
- http://view.ncbi.nlm.nih.gov/pubmed/18619730
- Print-ISSN:
- 0304-3835
- TUM Einrichtung:
- Institut für Allgemeine Pathologie und Pathologische Anatomie
BibTeX