Empere, Marta;Wang, Xujia;Prein, Carina;Aspberg, Anders;Moser, Markus;Oohashi, Toshitaka;Clausen-Schaumann, Hauke;Aszodi, Attila;Alberton, Paolo
Aggrecan governs intervertebral discs development by providing critical mechanical cues of the extracellular matrix.
Front Bioeng Biotechnol
2023
11

Rohwedder, Ina;Wackerbarth, Lou Martha;Heinig, Kristina;Ballweg, Annamaria;Altstätter, Johannes;Ripphahn, Myriam;Nussbaum, Claudia;Salvermoser, Melanie;Bierschenk, Susanne;Straub, Tobias;Gunzer, Matthias;Schmidt-Supprian, Marc;Kolben, Thomas;Schulz, Christian;Ma, Averil;Walzog, Barbara;Heinig, Matthias;Sperandio, Markus
A20 and the noncanonical NF-κB pathway are key regulators of neutrophil recruitment during fetal ontogeny.
JCI Insight
2023
8
4

Kaltenbach, Lukas;Martzloff, Paloma;Bambach, Sarah K;Aizarani, Nadim;Mihlan, Michael;Gavrilov, Alina;Glaser, Katharina M;Stecher, Manuel;Thünauer, Roland;Thiriot, Aude;Heger, Klaus;Kierdorf, Katrin;Wienert, Stephan;von Andrian, Ulrich H;Schmidt-Supprian, Marc;Nerlov, Claus;Klauschen, Frederick;Roers, Axel;Bajénoff, Marc;Grün, Dominic;Lämmermann, Tim
Slow integrin-dependent migration organizes networks of tissue-resident mast cells.
Nat Immunol
2023
24
6
915-924

Pruenster, Monika;Immler, Roland;Roth, Jonas;Kuchler, Tim;Bromberger, Thomas;Napoli, Matteo;Nussbaumer, Katrin;Rohwedder, Ina;Wackerbarth, Lou Martha;Piantoni, Chiara;Hennis, Konstantin;Fink, Diana;Kallabis, Sebastian;Schroll, Tobias;Masgrau-Alsina, Sergi;Budke, Agnes;Liu, Wang;Vestweber, Dietmar;Wahl-Schott, Christian;Roth, Johannes;Meissner, Felix;Moser, Markus;Vogl, Thomas;Hornung, Veit;Broz, Petr;Sperandio, Markus
E-selectin-mediated rapid NLRP3 inflammasome activation regulates S100A8/S100A9 release from neutrophils via transient gasdermin D pore formation.
Nat Immunol
2023
24
12
2021-2031

Uhl, Bernd;Haring, Florian;Slotta-Huspenina, Julia;Luft, Joshua;Schneewind, Vera;Hildinger, Jonas;Wu, Zhengquan;Steiger, Katja;Smiljanov, Bojan;Batcha, Aarif M N;Keppler, Oliver T;Hellmuth, Johannes C;Lahmer, Tobias;Stock, Konrad;Weiss, Bernhard G;Canis, Martin;Stark, Konstantin;Bromberger, Thomas;Moser, Markus;Schulz, Christian;Weichert, Wilko;Zuchtriegel, Gabriele;Reichel, Christoph A
Vitronectin promotes immunothrombotic dysregulation in the venular microvasculature.
Front Immunol
2023
14

Singh, Anurag Kumar;Rai, Amrita;Weber, Anja;Gericke, Martin;Janssen, Klaus-Peter;Moser, Markus;Posern, Guido
MRTF-A gain-of-function in mice impairs homeostatic renewal of the intestinal epithelium.
Cell Death Dis
2023
14
9

Fischer, Anja;Lersch, Robert;de Andrade Krätzig, Niklas;Strong, Alexander;Friedrich, Mathias J;Weber, Julia;Engleitner, Thomas;Öllinger, Rupert;Yen, Hsi-Yu;Kohlhofer, Ursula;Gonzalez-Menendez, Irene;Sailer, David;Kogan, Liz;Lahnalampi, Mari;Laukkanen, Saara;Kaltenbacher, Thorsten;Klement, Christine;Rezaei, Majdaddin;Ammon, Tim;Montero, Juan J;Schneider, Günter;Mayerle, Julia;Heikenwälder, Mathias;Schmidt-Supprian, Marc;Quintanilla-Martinez, Leticia;Steiger, Katja;Liu, Pentao;Cadiñanos, Juan;Vassiliou, George S;Saur, Dieter;Lohi, Olli;Heinäniemi, Merja;Conte, Nathalie;Bradley, Allan;Rad, Lena;Rad, Roland
In vivo interrogation of regulatory genomes reveals extensive quasi-insufficiency in cancer evolution.
Cell Genom
2023
3
3

Griger, Joscha;Widholz, Sebastian A;Jesinghaus, Moritz;de Andrade Krätzig, Niklas;Lange, Sebastian;Engleitner, Thomas;Montero, Juan José;Zhigalova, Ekaterina;Öllinger, Rupert;Suresh, Veveeyan;Winkler, Wiebke;Lier, Svenja;Baranov, Olga;Trozzo, Riccardo;Ben Khaled, Najib;Chakraborty, Shounak;Yu, Jiakun;Konukiewitz, Björn;Steiger, Katja;Pfarr, Nicole;Rajput, Ashish;Sailer, David;Keller, Gisela;Schirmacher, Peter;Röcken, Christoph;Fagerstedt, Klaus W;Mayerle, Julia;Schmidt-Supprian, Marc;Schneider, Günter;Weichert, Wilko;Calado, Dinis P;Sommermann, Thomas;Klöppel, Günter;Rajewsky, Klaus;Saur, Dieter;Rad, Roland
An integrated cellular and molecular model of gastric neuroendocrine cancer evolution highlights therapeutic targets.
Cancer Cell
2023
41
7
1327-1344.e10

Falcomatà, Chiara;Bärthel, Stefanie;Schneider, Günter;Rad, Roland;Schmidt-Supprian, Marc;Saur, Dieter
Context-Specific Determinants of the Immunosuppressive Tumor Microenvironment in Pancreatic Cancer.
Cancer Discov
2023
13
2
278-297

Borza, Corina M;Bolas, Gema;Zhang, Xiuqi;Browning Monroe, Mary Beth;Zhang, Ming-Zhi;Meiler, Jens;Skwark, Marcin J;Harris, Raymond C;Lapierre, Lynne A;Goldenring, James R;Hook, Magnus;Rivera, Jose;Brown, Kyle L;Leitinger, Birgit;Tyska, Matthew J;Moser, Markus;Böttcher, Ralph T;Zent, Roy;Pozzi, Ambra
The Collagen Receptor Discoidin Domain Receptor 1b Enhances Integrin β1-Mediated Cell Migration by Interacting With Talin and Promoting Rac1 Activation.
Front Cell Dev Biol
2022
10