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The Collagen Receptor Discoidin Domain Receptor 1b Enhances Integrin β1-Mediated Cell Migration by Interacting With Talin and Promoting Rac1 Activation.
Front Cell Dev Biol
2022
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Jäkel, Heidelinde;Taschler, Martin;Jung, Karin;Weinl, Christina;Pegka, Fragka;Kullmann, Michael Keith;Podmirseg, Silvio Roland;Dutta, Sayantanee;Moser, Markus;Hengst, Ludger
Inability to phosphorylate Y88 of p27Kip1 enforces reduced p27 protein levels and accelerates leukemia progression.
Leukemia
2022
36
7
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Wen, Lai;Moser, Markus;Ley, Klaus
Molecular mechanisms of leukocyte β2 integrin activation.
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2022
139
24
3480-3492

Lu, Fan;Zhu, Liang;Bromberger, Thomas;Yang, Jun;Yang, Qiannan;Liu, Jianmin;Plow, Edward F;Moser, Markus;Qin, Jun
Mechanism of integrin activation by talin and its cooperation with kindlin.
Nat Commun
2022
13
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Petzold, Tobias;Zhang, Zhe;Ballesteros, Iván;Saleh, Inas;Polzin, Amin;Thienel, Manuela;Liu, Lulu;Ul Ain, Qurrat;Ehreiser, Vincent;Weber, Christian;Kilani, Badr;Mertsch, Pontus;Götschke, Jeremias;Cremer, Sophie;Fu, Wenwen;Lorenz, Michael;Ishikawa-Ankerhold, Hellen;Raatz, Elisabeth;El-Nemr, Shaza;Görlach, Agnes;Marhuenda, Esther;Stark, Konstantin;Pircher, Joachim;Stegner, David;Gieger, Christian;Schmidt-Supprian, Marc;Gaertner, Florian;Almendros, Isaac;Kelm, Malte;Schulz, Christian;Hidalgo, Andrés;Massberg, Steffen
Neutrophil "plucking" on megakaryocytes drives platelet production and boosts cardiovascular disease.
Immunity
2022
55
12
2285-2299.e7

Bromberger, Thomas;Klapproth, Sarah;Sperandio, Markus;Moser, Markus
Humanized β2 Integrin-Expressing Hoxb8 Cells Serve as Model to Study Integrin Activation.
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2022
11
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Mentz, Michael;Keay, William;Strobl, Carolin Dorothea;Antoniolli, Martina;Adolph, Louisa;Heide, Michael;Lechner, Axel;Haebe, Sarah;Osterode, Elisa;Kridel, Robert;Ziegenhain, Christoph;Wange, Lucas Esteban;Hildebrand, Johannes Adrian;Shree, Tanaya;Silkenstedt, Elisabeth;Staiger, Annette M;Ott, German;Horn, Heike;Szczepanowski, Monika;Richter, Julia;Levy, Ronald;Rosenwald, Andreas;Enard, Wolfgang;Zimber-Strobl, Ursula;von Bergwelt-Baildon, Michael;Hiddemann, Wolfgang;Klapper, Wolfram;Schmidt-Supprian, Marc;Rudelius, Martina;Bararia, Deepak;Passerini, Verena;Weigert, Oliver
PARP14 is a novel target in STAT6 mutant follicular lymphoma.
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2022
36
9
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Immler, Roland;Nadolni, Wiebke;Bertsch, Annika;Morikis, Vasilios;Rohwedder, Ina;Masgrau-Alsina, Sergi;Schroll, Tobias;Yevtushenko, Anna;Soehnlein, Oliver;Moser, Markus;Gudermann, Thomas;Barnea, Eytan R;Rehberg, Markus;Simon, Scott I;Zierler, Susanna;Pruenster, Monika;Sperandio, Markus
The voltage-gated potassium channel KV1.3 regulates neutrophil recruitment during inflammation.
Cardiovasc Res
2022
118
5
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Schneeweis, Christian;Diersch, Sandra;Hassan, Zonera;Krauß, Lukas;Schneider, Carolin;Lucarelli, Daniele;Falcomatà, Chiara;Steiger, Katja;Öllinger, Rupert;Krämer, Oliver H;Arlt, Alexander;Grade, Marian;Schmidt-Supprian, Marc;Hessmann, Elisabeth;Wirth, Matthias;Rad, Roland;Reichert, Maximilian;Saur, Dieter;Schneider, Günter
AP1/Fra1 confers resistance to MAPK cascade inhibition in pancreatic cancer.
Cell Mol Life Sci
2022
80
1

Kaltenbacher, Thorsten;Löprich, Jessica;Maresch, Roman;Weber, Julia;Müller, Sebastian;Oellinger, Rupert;Groß, Nina;Griger, Joscha;de Andrade Krätzig, Niklas;Avramopoulos, Petros;Ramanujam, Deepak;Brummer, Sabine;Widholz, Sebastian A;Bärthel, Stefanie;Falcomatà, Chiara;Pfaus, Anja;Alnatsha, Ahmed;Mayerle, Julia;Schmidt-Supprian, Marc;Reichert, Maximilian;Schneider, Günter;Ehmer, Ursula;Braun, Christian J;Saur, Dieter;Engelhardt, Stefan;Rad, Roland
CRISPR somatic genome engineering and cancer modeling in the mouse pancreas and liver.
Nat Protoc
2022
17
4
1142-1188