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Title:

Amyotrophic Lateral Sclerosis and swim training affect copper metabolism in skeletal muscle in a mouse model of disease.

Document type:
Journal Article
Author(s):
Białobrodzka, Emilia; Flis, Damian Jozef; Akdogan, Banu; Borkowska, Andzelika; Wieckowski, Mariusz Roman; Antosiewicz, Jedrzej; Zischka, Hans; Dzik, Katarzyna Patrycja; Kaczor, Jan Jacek; Ziolkowski, Wieslaw
Abstract:
INTRODUCTION/AIMS: Swim training and regulation of copper metabolism result in clinical benefits in amyotrophic lateral sclerosis (ALS) mice. Therefore, the study aimed to determine whether swim training improves copper metabolism by modifying copper metabolism in the skeletal muscles of ALS mice. METHODS: SOD1G93A mice (n = 6 per group) were used as the ALS model, and wild-type B6SJL (WT) mice as controls (n = 6). Mice with ALS were analyzed before the onset of ALS (ALS BEFORE), at baseline ALS...     »
Journal title abbreviation:
Muscle Nerve
Year:
2024
Journal volume:
70
Journal issue:
5
Pages contribution:
1111-1118
Fulltext / DOI:
doi:10.1002/mus.28237
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/39225106
Print-ISSN:
0148-639X
TUM Institution:
Institut für Toxikologie und Umwelthygiene (Prof. Göttlicher)
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