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Title:

A fluorometric assay to determine labile copper(II) ions in serum.

Document type:
Journal Article; Research Support, Non-U.S. Gov't
Author(s):
Maares, Maria; Haupt, Alessia; Schüßler, Christoph; Kulike-Koczula, Marcel; Hackler, Julian; Keil, Claudia; Mohr, Isabelle; Schomburg, Lutz; Süssmuth, Roderich D; Zischka, Hans; Merle, Uta; Haase, Hajo
Abstract:
Labile copper(II) ions (Cu2+) in serum are considered to be readily available for cellular uptake and to constitute the biologically active Cu2+ species in the blood. It might also be suitable to reflect copper dyshomeostasis during diseases such as Wilson's disease (WD) or neurological disorders. So far, no direct quantification method has been described to determine this small Cu2+ subset. This study introduces a fluorometric high throughput assay using the novel Cu2+ binding fluoresceine-pept...     »
Journal title abbreviation:
Sci Rep
Year:
2023
Journal volume:
13
Journal issue:
1
Fulltext / DOI:
doi:10.1038/s41598-023-39841-9
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/37550465
Print-ISSN:
2045-2322
TUM Institution:
Institut für Toxikologie und Umwelthygiene
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