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Title:

Crystal structure of MbnF: an NADPH-dependent flavin monooxygenase from Methylocystis strain SB2.

Document type:
Journal Article
Author(s):
Stewart, Andrew; Dershwitz, Philip; Stewart, Charles; Sawaya, Michael R; Yeates, Todd O; Semrau, Jeremy D; Zischka, Hans; DiSpirito, Alan A; Bobik, Thomas A
Abstract:
Methanobactins (MBs) are ribosomally produced and post-translationally modified peptides (RiPPs) that are used by methanotrophs for copper acquisition. The signature post-translational modification of MBs is the formation of two heterocyclic groups, either an oxazolone, pyrazinedione or imidazolone group, with an associated thioamide from an X-Cys dipeptide. The precursor peptide (MbnA) for MB formation is found in a gene cluster of MB-associated genes. The exact biosynthetic pathway of MB forma...     »
Journal title abbreviation:
Acta Crystallogr F Struct Biol Commun
Year:
2023
Journal volume:
79
Journal issue:
Pt 5
Pages contribution:
111-118
Fulltext / DOI:
doi:10.1107/S2053230X23003035
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/37158309
Print-ISSN:
2053-230X
TUM Institution:
Institut für Toxikologie und Umwelthygiene
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