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Titel:

Amyotrophic Lateral Sclerosis and swim training affect copper metabolism in skeletal muscle in a mouse model of disease.

Dokumenttyp:
Journal Article
Autor(en):
Białobrodzka, Emilia; Flis, Damian Jozef; Akdogan, Banu; Borkowska, Andzelika; Wieckowski, Mariusz Roman; Antosiewicz, Jedrzej; Zischka, Hans; Dzik, Katarzyna Patrycja; Kaczor, Jan Jacek; Ziolkowski, Wieslaw
Abstract:
INTRODUCTION/AIMS: Swim training and regulation of copper metabolism result in clinical benefits in amyotrophic lateral sclerosis (ALS) mice. Therefore, the study aimed to determine whether swim training improves copper metabolism by modifying copper metabolism in the skeletal muscles of ALS mice. METHODS: SOD1G93A mice (n = 6 per group) were used as the ALS model, and wild-type B6SJL (WT) mice as controls (n = 6). Mice with ALS were analyzed before the onset of ALS (ALS BEFORE), at baseline ALS...     »
Zeitschriftentitel:
Muscle Nerve
Jahr:
2024
Band / Volume:
70
Heft / Issue:
5
Seitenangaben Beitrag:
1111-1118
Volltext / DOI:
doi:10.1002/mus.28237
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/39225106
Print-ISSN:
0148-639X
TUM Einrichtung:
Institut für Toxikologie und Umwelthygiene (Prof. Göttlicher)
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