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Titel:

Deadly excess copper.

Dokumenttyp:
Journal Article; Review
Autor(en):
Sailer, Judith; Nagel, Judith; Akdogan, Banu; Jauch, Adrian T; Engler, Jonas; Knolle, Percy A; Zischka, Hans
Abstract:
Higher eukaryotes' life is impossible without copper redox activity and, literally, every breath we take biochemically demonstrates this. However, this dependence comes at a considerable price to ensure target-oriented copper action. Thereto its uptake, distribution but also excretion are executed by specialized proteins with high affinity for the transition metal. Consequently, malfunction of copper enzymes/transporters, as is the case in hereditary Wilson disease that affects the intracellular...     »
Zeitschriftentitel:
Redox Biol
Jahr:
2024
Band / Volume:
75
Volltext / DOI:
doi:10.1016/j.redox.2024.103256
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/38959622
TUM Einrichtung:
Institut für Toxikologie und Umwelthygiene (Prof. Göttlicher)
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