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Title:

mGluR1/TRPC3-mediated Synaptic Transmission and Calcium Signaling in Mammalian Central Neurons.

Document type:
Journal Article; Review
Author(s):
Hartmann, J; Henning, HA; Konnerth, A
Abstract:
Metabotropic glutamate receptors type 1 (mGluR1s) are required for a normal function of the mammalian brain. They are particularly important for synaptic signaling and plasticity in the cerebellum. Unlike ionotropic glutamate receptors that mediate rapid synaptic transmission, mGluR1s produce in cerebellar Purkinje cells a complex postsynaptic response consisting of two distinct signal components, namely a local dendritic calcium signal and a slow excitatory postsynaptic potential. The basic mec...     »
Journal title abbreviation:
Cold Spring Harb Perspect Biol
Year:
2011
Journal volume:
3
Journal issue:
4
Language:
eng
Fulltext / DOI:
doi:10.1101/cshperspect.a006726
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/21441586
Print-ISSN:
1943-0264
TUM Institution:
Institut für Neurowissenschaften
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