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Titel:

Cell-type-specific modulation of targets and distractors by dopamine D1 receptors in primate prefrontal cortex.

Dokumenttyp:
Journal Article; Article
Autor(en):
Jacob, Simon N; Stalter, Maximilian; Nieder, Andreas
Abstract:
The prefrontal cortex (PFC) is crucial for maintaining relevant information in working memory and resisting interference. PFC neurons are strongly regulated by dopamine, but it is unknown whether dopamine receptors are involved in protecting target memories from distracting stimuli. We investigated the prefrontal circuit dynamics and dopaminergic modulation of targets and distractors in monkeys trained to ignore interfering stimuli in a delayed-match-to-numerosity task. We found that dopamine D1...     »
Zeitschriftentitel:
Nat Commun
Jahr:
2016
Band / Volume:
7
Seitenangaben Beitrag:
13218
Sprache:
eng
Volltext / DOI:
doi:10.1038/ncomms13218
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/27807366
Print-ISSN:
2041-1723
TUM Einrichtung:
Institut für Neurowissenschaften
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