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Titel:

mGluR1/TRPC3-mediated Synaptic Transmission and Calcium Signaling in Mammalian Central Neurons.

Dokumenttyp:
Journal Article; Review
Autor(en):
Hartmann, J; Henning, HA; Konnerth, A
Abstract:
Metabotropic glutamate receptors type 1 (mGluR1s) are required for a normal function of the mammalian brain. They are particularly important for synaptic signaling and plasticity in the cerebellum. Unlike ionotropic glutamate receptors that mediate rapid synaptic transmission, mGluR1s produce in cerebellar Purkinje cells a complex postsynaptic response consisting of two distinct signal components, namely a local dendritic calcium signal and a slow excitatory postsynaptic potential. The basic mec...     »
Zeitschriftentitel:
Cold Spring Harb Perspect Biol
Jahr:
2011
Band / Volume:
3
Heft / Issue:
4
Sprache:
eng
Volltext / DOI:
doi:10.1101/cshperspect.a006726
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/21441586
Print-ISSN:
1943-0264
TUM Einrichtung:
Institut für Neurowissenschaften
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