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Endothelial deletion of the cytochrome P450 reductase (POR) leads to cardiac remodeling
J Vasc Res
2023
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Fischer, Maximillian;Jakab, Moritz;Hirt, Marc N;Werner, Tessa R;Engelhardt, Stefan;Sarikas, Antonio
Identification of hypertrophy-modulating Cullin-RING ubiquitin ligases in primary cardiomyocytes.
Front Physiol
2023
14

Maus, Mate;López-Polo, Vanessa;Mateo, Lidia;Lafarga, Miguel;Aguilera, Mònica;De Lama, Eugenia;Meyer, Kathleen;Sola, Anna;Lopez-Martinez, Cecilia;López-Alonso, Ines;Guasch-Piqueras, Marc;Hernandez-Gonzalez, Fernanda;Chaib, Selim;Rovira, Miguel;Sanchez, Mayka;Faner, Rosa;Agusti, Alvar;Diéguez-Hurtado, Rodrigo;Ortega, Sagrario;Manonelles, Anna;Engelhardt, Stefan;Monteiro, Freddy;Stephan-Otto Attolini, Camille;Prats, Neus;Albaiceta, Guillermo;Cruzado, Josep M;Serrano, Manuel
Iron accumulation drives fibrosis, senescence and the senescence-associated secretory phenotype.
Nat Metab
2023
5
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Schröper, Tobias;Mehrkens, Dennis;Leiss, Veronika;Tellkamp, Frederik;Engelhardt, Stefan;Herzig, Stefan;Birnbaumer, Lutz;Nürnberg, Bernd;Matthes, Jan
Protective effects of Gαi3 deficiency in a murine heart-failure model of β1-adrenoceptor overexpression.
Naunyn Schmiedebergs Arch Pharmacol
2024
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Haberman, Emma R;Sarker, Gitalee;Arús, Bernardo A;Ziegler, Karin A;Meunier, Sandro;Martínez-Sánchez, Noelia;Freibergerová, Eliška;Yilmaz-Özcan, Sinem;Fernández-González, Iara;Zentai, Chloe;O'Brien, Conan J O;Grainger, David E;Sidarta-Oliveira, Davi;Chakarov, Svetoslav;Raimondi, Andrea;Iannacone, Matteo;Engelhardt, Stefan;López, Miguel;Ginhoux, Florent;Domingos, Ana I
Immunomodulatory leptin receptor+ sympathetic perineurial barrier cells protect against obesity by facilitating brown adipose tissue thermogenesis.
Immunity
2024
57
1
141-152.e5

Ziegler, Karin A;Ahles, Andrea;Dueck, Anne;Esfandyari, Dena;Pichler, Pauline;Weber, Karolin;Kotschi, Stefan;Bartelt, Alexander;Sinicina, Inga;Graw, Matthias;Leonhardt, Heinrich;Weckbach, Ludwig T;Massberg, Steffen;Schifferer, Martina;Simons, Mikael;Hoeher, Luciano;Luo, Jie;Ertürk, Ali;Schiattarella, Gabriele G;Sassi, Yassine;Misgeld, Thomas;Engelhardt, Stefan
Immune-mediated denervation of the pineal gland underlies sleep disturbance in cardiac disease.
Science
2023
381
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Beck, Christina;Ramanujam, Deepak;Vaccarello, Paula;Widenmeyer, Florenc;Feuerherd, Martin;Cheng, Cho-Chin;Bomhard, Anton;Abikeeva, Tatiana;Schädler, Julia;Sperhake, Jan-Peter;Graw, Matthias;Safi, Seyer;Hoffmann, Hans;Staab-Weijnitz, Claudia A;Rad, Roland;Protzer, Ulrike;Frischmuth, Thomas;Engelhardt, Stefan
Trimannose-coupled antimiR-21 for macrophage-targeted inhalation treatment of acute inflammatory lung damage.
Nat Commun
2023
14
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Laggerbauer, Bernhard;Engelhardt, Stefan
MicroRNAs as therapeutic targets in cardiovascular disease.
J Clin Invest
2022
132
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Warwick, Timothy;Seredinski, Sandra;Krause, Nina M;Bains, Jasleen Kaur;Althaus, Lara;Oo, James A;Bonetti, Alessandro;Dueck, Anne;Engelhardt, Stefan;Schwalbe, Harald;Leisegang, Matthias S;Schulz, Marcel H;Brandes, Ralf P
A universal model of RNA.DNA:DNA triplex formation accurately predicts genome-wide RNA-DNA interactions.
Brief Bioinform
2022
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Lopez, Melina;Malacarne, Pedro F;Ramanujam, Deepak P;Warwick, Timothy;Müller, Niklas;Hu, Jiong;Dewenter, Matthias;Weigert, Andreas;Günther, Stefan;Gilsbach, Ralf;Engelhardt, Stefan;Brandes, Ralf P;Rezende, Flávia
Endothelial deletion of the cytochrome P450 reductase leads to cardiac remodelling.
Front Physiol
2022
13