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Titel:

Perioperative Low-Dose Prednisolone Treatment Has Beneficial Effects on Postoperative Recovery and Anastomotic Healing in a Murine Colitis Model.

Dokumenttyp:
Journal Article
Autor(en):
Weber, Marie-Christin; Bauer, Jannick; Buck, Annalisa; Clees, Zoé; Oertel, Reinhard; Kasajima, Atsuko; Reischl, Stefan; Wilhelm, Dirk; Friess, Helmut; Neumann, Philipp-Alexander
Abstract:
BACKGROUND AND AIMS: High-dose glucocorticoid treatment has been identified as a risk factor for anastomotic leakage in patients with inflammatory bowel disease [IBD] undergoing bowel resection surgery. By contrast, active disease during surgery is also associated with elevated morbidity. Perioperative low-dose treatment might be beneficial regarding postoperative outcomes by controlling disease activity. The present study is the first to investigate the dose-dependent effect of perioperative pr...     »
Zeitschriftentitel:
J Crohns Colitis
Jahr:
2023
Band / Volume:
17
Heft / Issue:
6
Seitenangaben Beitrag:
950-959
Volltext / DOI:
doi:10.1093/ecco-jcc/jjad002
PubMed:
http://view.ncbi.nlm.nih.gov/pubmed/36638152
Print-ISSN:
1873-9946
TUM Einrichtung:
Institut für Allgemeine Pathologie und Pathologische Anatomie (Dr. Mogler komm.); Institut für Diagnostische und Interventionelle Radiologie (Prof. Makowski); Klinik und Poliklinik für Chirurgie (Prof. Friess)
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