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Title:

Superior Tumor Detection for 68Ga-FAPI-46 Versus 18F-FDG PET/CT and Conventional CT in Patients with Cholangiocarcinoma.

Document type:
Article; Observational Study; Journal Article; Research Support, Non-U.S. Gov't
Author(s):
Pabst, Kim M; Trajkovic-Arsic, Marija; Cheung, Phyllis F Y; Ballke, Simone; Steiger, Katja; Bartel, Timo; Schaarschmidt, Benedikt M; Milosevic, Aleksandar; Seifert, Robert; Nader, Michael; Kessler, Lukas; Siveke, Jens T; Lueckerath, Katharina; Kasper, Stefan; Herrmann, Ken; Hirmas, Nader; Schmidt, Hartmut H; Hamacher, Rainer; Fendler, Wolfgang P
Abstract:
Management of cholangiocarcinoma is among other factors critically determined by accurate staging. Here, we aimed to assess the accuracy of PET/CT with the novel cancer fibroblast-directed 68Ga-fibroblast activation protein (FAP) inhibitor (FAPI)-46 tracer for cholangiocarcinoma staging and management guidance. Methods: Patients with cholangiocarcinoma from a prospective observational trial were analyzed. 68Ga-FAPI-46 PET/CT detection efficacy was compared with 18F-FDG PET/CT and conventional CT...     »
Journal title abbreviation:
J Nucl Med
Year:
2023
Journal volume:
64
Journal issue:
7
Pages contribution:
1049-1055
Fulltext / DOI:
doi:10.2967/jnumed.122.265215
Pubmed ID:
http://view.ncbi.nlm.nih.gov/pubmed/37024301
Print-ISSN:
0161-5505
TUM Institution:
1404; 1413; Institut für Allgemeine Pathologie und Pathologische Anatomie (Dr. Mogler komm.)
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